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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a21d8beaafcdac917299331db8beb7ee92d55b7ce4b799cf2d0a87a20543ce5a' 
  AND token = 'pnxs7rnUnx6lsmG7itLXaZmqRFRnra7D/D/RYc7Ef3U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}