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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a8caa86cb65f0c49438c62c595d5a2527ff4fe284f36cc3bc6990a7e8d95e295' 
  AND token = 'kfE9yBt64wZUhX8lRvYfGkfEe2WXLJoqFB9fdOpoRIQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}