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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b877e26a2a3bf678295e8f007fce6ac3eaa5c996607cf97fa346c1086bae3359' 
  AND token = 'LwN/4riQ82tIBY/eg/gj4tk5VlBH1Dhzrnd1oEYnn8E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}