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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '904bbd7ab5716a091dc0b57ff63f52a83c4a449691703077c924e36c9e3a2c42' 
  AND token = 'trSCWn/NCXaBrPmhp5Bl7nZUSmnYHzSVGYdME98PyIE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}