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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fe8aa5d09653663ea648f2b835007aeb68598003d427a5ac7a05b6811e198f80' 
  AND token = 'hUUKmko4R88GadiAs5KYlePX1IZuEGtrDKaOxU2ZB9Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}