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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9b66992688ae60ed2f52e1073a0364780ece69fe35eb54add6f07a6fbc5fb43e' 
  AND token = 'DBLxNbdkAHGThQETwMPqZ8RXgDPDAfOFa9ycPfwfwVo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}