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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '246477c81a1d147d8ccc356ad0e6bf19712276b6856668884169b917afa8aab0' 
  AND token = 'MnHL5LoV1VC07bBpq+DesUKxBs8H5IBUSK3MEKEBdVw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}