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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '17d7782937e06a897148fe4143923d6198cb442bfc823bf90c0351138543a518' 
  AND token = 'SAzYmPm/0HE/0oJy5lUVqaQuD7qkmuFyg72ZsFWTz4o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}