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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a0463d4691b9632185319ca25a40b6296801c113236223fdeb7bf7aa7f1dc379' 
  AND token = 'EAu7o3xI7JxSueeMEe1Yc8gwJFcuVhn1+RcPlo/vbDE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}