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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3072a0addb3e5aed1f10eb7b545c5ed67295d3d528ebfb44b65cf38a51eef340' 
  AND token = 'IiH15G2ekY/HHC1vBldWk6ijZycZZxHUgV+e9AVO2Hw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}