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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0babc709e2cc64a74e4b352b0ca8c39bb03e078e2093c9ed6359702678b88435' 
  AND token = 'xK7iMAIi/xnNB/I/cKmWjrwfzV+Hpy3py4OuMj6xZzc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}