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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65775045c9b282a38bc0791c75e1b45329b04167d00b0c8cafd4f8802984accd' 
  AND token = 'notTaW9zMnL/yW6cgTYfaV7OjebcTa1zUDdPkJI9Z9w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}