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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'afca49f357db3ea4740bf3bc25572f5ca9f5685ec6f541d3b9f0fd16d1d7d620' 
  AND token = '0rwHCo3RstXALlcHHHDEmlnU5TIY8kDUFLFCKhIGaw0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}