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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec3a7fee03c7e07102d59d893bd9bccf77a5c774e421d12ed983017750caedcc' 
  AND token = 'x1dpd6hI1o+TR4HnB6NvZDXmZcHPJYatFgFzgPGhoy8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}