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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a55dc80bf7e6d0532a5af9e3d9eb810d6e78eb405eb76242f6a80d225c55b36e' 
  AND token = 'JOosnFZH7JfD/vE9oSzRvpwNE7T5qUX3vmmO2DA/OQQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}