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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '15ff9a1019b00800da1027107fbac41e1d6289660f167c1723e8b5507d8a7c05' 
  AND token = 'JMZl0JHi8d57HyfVzFYYFv2Zi6zHtvVHilasNWUcmSA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}