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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '86f353173e1c23e4457d4cf4d38b919069e159a03e6a34f220bacee89d2dba5f' 
  AND token = 'GmPGQOBrEOm9OJzrstrILMgT8euyKW2HAsEfWuXe6Ss=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}