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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1fa15e6dc4733192d84035d20779ddf2cec1a20f8bb80ecd2c194e7d68af4cec' 
  AND token = 'NIZL6dvXOPpD1pYYBrGCs9yxeVve24ULyS57kItq380=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}