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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a1385baf314e30d3bd88ca84eab84913e0e8d8ca745ac5e66cc0f00db255a0f' 
  AND token = '1/owyCQG4EzhPMOI45h2GFzap8wsL68GaeZ38f/pYyM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}