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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bb5b65890443058ce8b1de8a6b980e750dd1aceeefbd7ecc36070c5346e1dbcd' 
  AND token = 'ZyeZU3pF7oCorn7bOeZj4Y0wUhW+rOvjUpPsd3FQUwI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}