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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c8f6fb627c004541195294093f4db3ef0ff23f2352c026b680a86a9c490bb659' 
  AND token = 'Wuw221mVzuE9qOte73294ityhOaX2onsuabWyRAO2AA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}