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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '85aa4cb4421bf75cd5095de64565c80dd31251f617241dc75f3fda44d59b63a8' 
  AND token = '43A01+b3/I1O9vBpB2MLlP4xCULLevyt/cmQoCm0gRE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}