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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ad6ecaf2c5ded0a8dbf1a209cbca3806756dfba3893ac396c0b4fed2e0d0f1c' 
  AND token = 'MiES8VJiIqkZI08+E77hxh+WInciuz8/3nx1d/blXAs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}