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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bf5f2521337d95a8f5bf21dbac5688a802eb65582da135321ce75188dd558857' 
  AND token = 'wUWONzfifqavs0CTqoXY0tLjjQeJPe2/gVLxnz/6jkA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}