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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22a6155a1b56188f0998f3f94ec1154a659f48e488eaafa81e9f28b9185f5d27' 
  AND token = '9FhScLW+lRyglz2XS6ddzL6DzoySq/i4vFCgl6mSWgo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}