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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '125d19ca7ec59d3878259c0fb373f6caf2e7f95036877504a38fc1df37ccf0f8' 
  AND token = 'YVVOx+crBsneqcw4w8yXLnFvqooVH6t02c8olh5QiSo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}