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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6181751dd374dbc30a2686f713308924a573bbdded4ea16a3eb92d38225f4f8c' 
  AND token = 'hoR83rh6dA9DsY3F0Ms4+SYgOJ4Ruzfu+LqYpLD8qTU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}