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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22f2d576234ceefb15dfb35d2d5a9cbf7383f8a058cccb17c079d218c15cab24' 
  AND token = 'Dm5q43dHmygXi6VZCyD+0etJyuFnttHjDHk4Rc3zURk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}