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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad2be3208f35d8437de6c2839dd9f5365a81c02a20a6640024f5c6992bcad895' 
  AND token = 'r4sBgXio56OEVj0dvAXqGeNBI8OAxOK+QrIOQ1BHfE0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}