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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '67933f52c3e3493d42c808c57217cb72df42781537f48cb726596b02eaf83f50' 
  AND token = 'I5X71Jm5zjQemYV0AVyACWtjDIqTqLoU5OmpiZa1jE4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}