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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '244f74041a8e01dc2c369224efa7c0916aa1eef7eca3775831db3da0e6697c9c' 
  AND token = 'RqV+CsAZP7b+FSd2GH75MgmnCtB/XdFzQ3ziBxDCk1Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}