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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c8b97aed837f86acc8a6e54aed2fbdb3c4b6f84078c6ee583caab6c739e25d1' 
  AND token = 'nu6B0fMxoQkoenpQZZXXX7YYOjH2uyPlzdqF1BeXfRo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}