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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e9b2a7e788428fa790404f9f011e8a3fb20a48bb5acc0fc7098eed96e630216' 
  AND token = 'WXrn9hO9oE0SMs8oNNwdoSFE/mC41sYq+vd2kIqwJeA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}