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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66fd0cdf1d65142f0e446a35cc29f8e8e8b5dd347c04fa6e4b9420dc62063fba' 
  AND token = 'oXtLUbZLWjWEy7P3C378hueynikn9lzt+3THqgoRCcI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}