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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '58d3b6e4f8bf992ce6de40ece80646a4512a1d234430c57528042d4ed70db50a' 
  AND token = 'El0VpQyG11FUWgeD+B1h6eTCbswt1nPoO1CCj+A+XnI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}