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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf8f951ef460ccd3bc9e1bfc0445ca1350e43e8f154d50a03419067f16b503b0' 
  AND token = '7trwhckg+RvnV7qMp8S0QIYQdVRrnVOYwQz1zTgcCZk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}