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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'db0f39c58b75647cfaaf7e57e52b7c431b5a163c2725ed6dd2ef0c8b733caf17' 
  AND token = 'MJ0d8SbZ5PpXeBH0txFeIWLRgxc6w8JsNo0HmPerCfA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}