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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78f3ddaf8abd53bf0a2e9e13d61130419913d93cf15e11a472d9c2a366cfd334' 
  AND token = '0fCvfb4PHa6OVL3061TZcR8Sv7dDmMF0U1ytIiSBRIo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}