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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a5edabc8306443b9e2a3f56dd62da17e3c1b4684ac7cc610c62d072bdd14592d' 
  AND token = 'UmXoDlWb4ASHNObVIHieMPOafnVbFM+lDe0NHC00LeM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}