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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a4fbd224203a812e53bd08d8f91a452a3fe0a2f4e614f25e3faa0b96b0d73299' 
  AND token = 'uL5VyY6gv8Rf1JZ504yW/QyFormrDoCtgzIJigMf21g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}