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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3fe9a00a49ff208ab2354353115903437dac6df86b7d8af2dfe3a188021b710c' 
  AND token = 'o0t7I6X5aU6aDYcyx/NGIuiFKIszyh6vOBbi8tqnt8Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}