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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bcf67ebdee274a5183c13f0b3a17f7e0609c4bb6f73dc3585ecfba5132f312fa' 
  AND token = 'JMYNJ85ZQ73O8wwqTP2hFvyUU0jsQJq/77HLJBFs8xI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}