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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12bf3b274f6f5be90e9ae301aa2c5d519dc6b593894a6a91a74ebd76a62551a4' 
  AND token = '2/2cuBykd2X41Jjx6UTFVwXO6FRnzreYcErcT9LSHZY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}