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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '235ea5a8ae439f50a108c5fa690f013991dc58df8ddd85b1d7f2d9fd909012ef' 
  AND token = 'p3gYtIv5Txwg/1SPHQ4nQilLqrvPYGP/4ptXtTahglg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}