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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c8c8fb39dfd00e2758eb7793a7795474b4ccebb837eeb1262be09e9c0e3107c' 
  AND token = 'WPaptC8X4iE7NG47FEM/whvuk5vf5M6F+WY2Obo91nE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}