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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f417de7eb270ba6f751d863f1203e60129d4972ec3dbd1a9072ee30175a06f2' 
  AND token = 'INYBp0AF57VbC1HaDdVspVsdSVqYPvqZ96BNxc7ZadQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}