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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7fda6a2b4a9863cb2096ec283f9e35522119a9b191c36ef6ffbad590fd0afc60' 
  AND token = 'x9NCq09/R9CR8Hc6dljyRLx9UmvzZ1kq4Rf7JD/z4uM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}