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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12cdafc561fa50ed16d9470b7cc93694111ba9645fb5d8fd099eae6e34a2d814' 
  AND token = 'rj8D3hcMO4g0shRkS8GM5/LwSOeVk36BV4pzLUEWg4U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}