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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e3f7bd67bd5353c271e2f80201c1b17b51749310c49ddc73c5c2a31ec6ace26' 
  AND token = 'moq3cIzV/IF3QoMViKZPE5gJAoPtEmxYpY43C+2xox4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}