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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c680e59f0aefd94d4b449d2da3c2649d376919ab854e6fe5b0251e781de98afb' 
  AND token = '9SkNQ8P4Cqf5h1avxpHL+fjQAeOBLFeKM1x76KJpvl0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}